NEB-related Nemaline myopathy is an inherited muscle disorder that typically affects muscles of the face, neck and limbs. There are six different types of Nemaline myopathy classified based on the age of the individual and the signs of the disorder. The most common type of this disorder is the typical congenital form and symptoms usually appear right after the baby is born or in the first year of life. They can have muscle weakness, feeding and breathing problems. Motor skills such as learning how to crawl and walk are delayed but most individuals with this type retain the ability to walk throughout their life. In most of the people with NEB-related Nemaline myopathy, the disease does not become worse over time, and most people with this form of the disorder are able to lead independent and active lives with the help of physical therapy. Intellect is not affected by nemaline myopathy. The typical congenital form of nemaline myopathy is caused by pathogenic variants in the NEB gene.