Familial Dysautonomia is an inherited disorder that affects the development and survival of specific types of cells in the nervous system. People who are born with familial dysautonomia have signs of the disease at birth. The nervous system of a person affected with familial dysautonomia will gradually get worse over time as well. Children affected with this disorder typically have low muscle strength. They can also have stomach and digestive problems, episodes of vomiting, and can have trouble breathing. They can have problems related to perception of pain and temperature. Children affected with familial dysautonomia will typically have delayed developmental milestones such as walking and speech. Individuals with familial dysautonomia have a decreased life expectancy when compared to people who do not have this disorder although medical surveillance and care may help to improve some symptoms and overall condition of life. Familial dysautonomia is caused by pathogenic variants in the IKBKAP gene.